Figure 2 | Scientific Reports

Figure 2

From: Pro-Cellular Exhaustion Markers are Associated with Splenic Microarchitecture Disorganization and Parasite Load in Dogs with Visceral Leishmaniasis

Figure 2

Identification of (A–C) IFN-γ+, (D–F) IL-10+, and (G–I) Ki-67+ cells by immunohistochemistry and quantitative analysis of the spleen of dogs naturally infected with L. infantum grouped according to the clinical score: (B) percentage of IFN-γ+ cells, (C) IFN-γ cells/mm2, (E) percentage of IL-10+ cells, (F) IL-10+ cells/mm2, (H) percentage of Ki-67+ cells and (I) Ki-67+ cells/mm2. Mann-Whitney test: (E) *p = 0.0409, **p = 0.0205. Kruskal-Wallis test: (E) p = 0.026.

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