Figure 5 | Scientific Reports

Figure 5

From: Pro-Cellular Exhaustion Markers are Associated with Splenic Microarchitecture Disorganization and Parasite Load in Dogs with Visceral Leishmaniasis

Figure 5

Gene expression of exhaustion markers in the spleen of dogs naturally infected with L. infantum. Ex vivo analysis by qPCR of the mRNA levels in the spleen of dogs classified according to the clinical score. Gene expression values were normalized to those of the constitutive genes HPRT and GAPDH. ANOVA: (A) p < 0.022. (*) Mann-Whitney test: (B) p < 0.036.

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