Figure 6 | Scientific Reports

Figure 6

From: Metagenomic analysis using next-generation sequencing of pathogens in bronchoalveolar lavage fluid from pediatric patients with respiratory failure

Figure 6

Phylogenetic analysis of enterovirus D68. Phylogenetic trees of full genomes (A) and VP1 sequences (B) of enterovirus D68 (EV-D68) consensus sequences obtained from patients 7 and 8 are shown. The phylogenetic relationships of the registered sequences of EV-D68 were estimated using the neighbor-joining method with 1,000 replicates using MEGA743. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test is shown next to the branches. The tree is drawn to scale, with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed using the p-distance method and are in units of the number of base differences per site. Clades were defined previously based on VP1 sequences37,50,51. GenBank accession number, strain name, country of origin, and year of detection are shown for each strain. Scale bars show the genetic distance.

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