Figure 6
From: Non-canonical transcriptional regulation of heme oxygenase in Aedes aegypti
Overview of the non-canonical and coupled with digestion transcriptional regulation of heme oxygenase in Aedes aegypti midgut. Schematic representation of a female of A. aegypti mosquito after a blood meal and in detail, the inside of a midgut cell – amino acids activate target-of-rapamycin (TOR) pathway, which induces the transcription of AeHO (presumably through the GATA factor) resulting in heme degradation and production of AeBV, thus contributing to gut homeostasis and hematophagic adaptation.
