Table 3 ANOVA test with Tukey’s multiple comparisons for structural and intrinsic mechanical properties of the right tibiae from control, sham, LI, MI and HI groups of rats derived from three-point bending tests of the mid-diaphysis.

From: High Impact Exercise Improves Bone Microstructure and Strength in Growing Rats

Parameters/Groups

Control

Sham

L.I.

M.I.

H.I.

Structural mechanical properties

Ultimate load, Fult (N)*

84.9 ± 13.3

80.1 ± 11.2

89.4 ± 9.22

93.5 ± 7.43 α

97.0 ± 8.16 α

Failure load, Ffail (N)

73.8 ± 11.6

67.3 ± 10.3

65.3 ± 10.6

63.4 ± 9.44

64.6 ± 9.82

Stiffness, k (N/mm)*

123 ± 18.7

113 ± 16.8

124 ± 15.8

135 ± 17.6 α

142 ± 15.8 α

Energy to ultimate load (mJ)

39.3 ± 5.7

35.3 ± 6.11

41.4 ± 6.82

42.2 ± 7.03

44.5 ± 7.26

Energy to failure load (mJ)*

55.2 ± 17.3

63.5 ± 15.2

77.6 ± 18.4

81.7 ± 14.8 α

79.8 ± 18.9 α

Intrinsic mechanical properties

Ultimate stress, σult (MPa)*

294 ± 44.5

286 ± 37.2

308 ± 52.1

319 ± 49.2 α

316 ± 38.2 α

Failure stress, σfail (MPa)*

223 ± 36.2

216 ± 21.2

187 ± 30.3

184 ± 26.2 α

186 ± 22.4 α

Young’s modulus, E (GPa)

10.9 ± 1.22

10.5 ± 1.46

11.2 ± 1.31

11.8 ± 1.01

12.3 ± 1.06

Energy to ultimate stress (mJ/mm3)

3.46 ± 1.11

2.71 ± 0.82

2.56 ± 0.96

2.89 ± 1.21

2.95 ± 0.85

Energy to failure stress (mJ/mm3)

8.37 ± 3.46

11.4 ± 4.17

11.7 ± 4.61

12.2 ± 3.19

11.9 ± 4.89

  1. Values are expressed as Mean ± SD, N = 6/group. In the parameter column, *indicates a significant effect (p < 0.05) from a one-way ANOVA with Tukey’s multiple comparisons test. When there was a significant effect, Tukey’s post-hoc pairwise comparisons evaluated whether the sham group was significantly different compared to the other groups [a bold value and ‘α’ indicate a significant difference versus sham group].