Table 3 Functions identified in the transcriptome and proteome of strain LA-SOL3 relevant for pathogenicity.

Siderophores

Iron-chelating ligands.

Iron transport compounds.

Intracellular iron storage compounds.

Suppress the growth of other microorganisms.

Renshaw et al.⁵⁰

Toxins

Polyketides that include a range of compounds as mycotoxins and spore pigments.

Toxic to plants and/or animals.

Mode of action extremely variable, depending on the produced compound.

Gaffoor et al.⁵¹

Chauhan et al.⁵²

Allergens

Sensitization with extraneous allergens.

Fugal allergens are usually proteins, polysaccharides, or glycoproteins.

IgE-mediated hypersensitivity in humans.

The major allergic manifestations are asthma, rhinitis, allergic bronchopulmonary mycoses, hypersensitivity pneumonitis.

Fukutomi & Taniguchi⁵³

MAPKs

Mitogen-activated protein kinases that function as key signal transduction components.

Fungal MAPKs help to promote the penetration of host tissues governing appressorium formation and virulence.

Hamel et al.¹⁸

He et al.²³

HSPs

Involved in several common biological activities, such as transcription, translation, protein folding, and aggregation and disaggregation of proteins.

Involved in stress response.

Different families of HSP are expressed depending on stress type, e.g.: pH, heat, cold or osmotic stress.

Tiwari et al.²¹

Nudix effectors

Maintenance of proper cellular processes and physiological homeostasis by sensing and modulation levels of their substrates like nucleotide sugars, deoxyribonucleoside triphosphate and capped mRNAs.

Manipulation of host defence systems.

Dong & Wang⁵⁴

Velvet complex

Regulation of fungal development and secondary metabolism.

Promotion of chromatin accessibility and expression of biosynthetic gene clusters involved pathogenicity as mycotoxins, pigments and hormones.

López-Berges et al.⁵⁵

Niehaus et al.²⁶