Figure 6 | Scientific Reports

Figure 6

From: Down-regulation of cyclin-dependent kinase 5 attenuates p53-dependent apoptosis of hippocampal CA1 pyramidal neurons following transient cerebral ischemia

Figure 6

Effects of roscovitine and IPC on Bax, Bcl-2, PUMA and caspase-3 (inactive and active form) levels in the TCI, roscovitine + TCI and IPC + TCI groups at sham, 1, 2 and 5 days after TCI. β-actin is used as a protein loading control. Relative band intensity of Bax, Bcl-2, PUMA and caspase-3 (inactive and active form) levels is measured by densitometer. Molecular weight is indicated as kDa on the right side of the immunoblots. The bars are reported as means ± SEM from three independent experiments (n = 7, *P < 0.05 vs. sham group; #P < 0.05 vs TCI group; †P < 0.05 vs roscovitine + TCI group).

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