Figure 2

Canonical pathways associated with the proliferative or secretory phases of the cycle in endocervix. (a) Pathways significantly changed in the proliferative vs. secretory phases. The y-axis displays the −log (p value) which was calculated by right-tailed Fisher’s exact test. The default cut off -log (p value) of 1.3 was applied. (−) z scores indicate down-regulation in the proliferative endocervix and (+) z scores indicate upregulation of the pathways in the proliferative endocervix. Some z scores were unavailable or unpredicted as the eligibility criteria of z score algorithm were not met. Ratio denotes the number of significantly changed genes compared with the total number of genes within the pathway. (b,c) Pathways identified by ORA using upregulated sets of DEGs in the proliferative (b) and secretory (c) phases.