Table 4 Comparison of the different TIL quantification methods based on their prognostic significance (logrank test based p-values) at different grid-cell sizes (smallest to largest).
Region Classifier | Quantification Methods | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
|---|---|---|---|---|---|---|---|---|---|
TRC-1 | Morisita-Horn (MH) | 0.1590 | 0.1610 | 0.1560 | 0.3250 | 0.2340 | 0.4760 | 0.4760 | 0.4760 |
Shannon Diversity (SD) | 0.1590 | 0.1610 | 0.1610 | 0.3250 | 0.2190 | 0.6550 | 0.4760 | 0.4760 | |
TILAb-MH | 0.0146 | 0.0258 | 0.0146 | 0.0012* | 0.0258 | 0.0006* | 0.0020* | 0.0006** | |
TILAb-SD | 0.0146 | 0.0146 | 0.0258 | 0.0146 | 0.0258 | 0.0258 | 0.0006** | 0.0006** | |
TRC-5 | Morisita-Horn (MH) | 0.0416 | 0.0666 | 0.1030 | 0.1800 | 0.0666 | 0.1800 | 0.2340 | 0.1790 |
Shannon Diversity (SD) | 0.0416 | 0.0666 | 0.0666 | 0.1160 | 0.0666 | 0.1800 | 0.2340 | 0.1790 | |
TILAb-MH | 0.0191 | 0.0191 | 0.0077* | 0.0077* | 0.0258 | 0.0236 | 0.0020* | 0.0038* | |
TILAb-SD | 0.0191 | 0.0359 | 0.0146 | 0.0258 | 0.0110 | 0.0146 | 0.0020* | 0.0020* |
