Figure 4

Alterations in gut microbiota composition in sIgAd subjects are durable across multiple timepoints. (a) Alpha diversity analyses of gut microbiota composition comparing initial and follow up stool samples from both healthy controls and sIgAd subjects as measured by observed OTU, Chao1, Simpson and Shannon Diversity Index. (b) Relative abundances of species level taxa from healthy controls and sIgAd subjects that had, in Fig. 2d, exhibited a significant difference between in relative abundance these two groups. (c) Bray-Curtis comparisons of initial and repeat samples from healthy control and IgA deficient subjects *p < 0.05, **p < 0.01, ***p < 0.001 by Mann Whitney U test.