Figure 3
Validation and re-validation of the candidate genes. (A) Corrected methylation levels of FGF5 and ZNF585A in the validation set. Differential methylation of only FGF5 was validated in the 21 responders and 13 non-responders. A horizontal dotted line shows a cut-off value for sensitivity and specificity obtained in the screening set, and whiskers show maximum and minimum methylation levels. (B) Corrected methylation levels of FGF5 in the re-validation set. Differential methylation of FGF5 was re-validated in the 26 responders and 16 non-responders. A horizontal dotted line shows a cut-off value for sensitivity and specificity obtained in the screening set, and whiskers show maximum and minimum methylation levels.
