Figure 4 | Scientific Reports

Figure 4

From: Comparative transcriptomics between species attributes reactogenicity pathways induced by the capsular group B meningococcal vaccine, 4CMenB, to the membrane-bound endotoxin of its outer membrane vesicle component

Figure 4

Global changes in gene expression at 24 hours. Euler plots of the total number of significantly differentially expressed genes (DEGs, FDR-adjusted p-value < 0.01) associated with each test group 24 hours after the second dose. (A) Overlap between DEGs associated with 4CMenB, and each of its alum-adsorbed components. (B) Overlap between 4CMenB, each of the alum-adsorbed deoxycholate and native outer membrane vesicles (dOMVs and nOMVs), and alum-adsorbed lipopolysaccharide (LPS) from Escherichia coli.

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