Table 4 Cancer detection results, obtained from ROC curves using all histological images’ patch-level statistics. Reported are the AUC for the validation group and the AUC, F1 score, accuracy, sensitivity, and specificity of the testing group with 95% confidence intervals for all values. Also shown in the right-most column is the ability of the proposed method to distinguish slides that contain cancer from slides that are all normal.

From: Head and Neck Cancer Detection in Digitized Whole-Slide Histology Using Convolutional Neural Networks

Group

Validation AUC

Test AUC

F1 Score

Accuracy

Sensitivity

Specificity

Slide Level AUC

SCC

0.913 (0.90,0.93)

0.916 (0.90, 0.93)

84.8 ± 1.5%

84.8 ± 1.6%

84.7 ± 2.2%

85.0 ± 2.2%

0.944 (0.91, 0.97)

Thyroid

0.927 (0.92, 0.94)

0.954 (0.94, 0.97)

89.4 ± 1.3%

89.4 ± 1.3%

89.6 ± 1.8%

89.1 ± 1.9%

0.995 (0.99, 1.00)

Lymph Node

0.986 (0.96, 0.99)

0.967 (0.96, 0.98)

91.8 ± 1.3%

93.4 ± 1.2%

90.1 ± 1.8%

93.6 ± 1.6%

0.901 (0.86, 0.94)