Table 1 Demographic and clinical characteristics of the women enrolled for the study, subdivided in healthy (HC), bacterial vaginosis (BV), C. trachomatis (CT), and vulvo-vaginal candidiasis (VVC) groups.
From: Diversity of vaginal microbiome and metabolome during genital infections
HC (N = 21) | BV (N = 20) | CT (N = 20) | VVC (N = 18) | P | |
|---|---|---|---|---|---|
Enrolment criteria | No symptoms and negative for microbiological tests | Positive for 3/4 Amsel criteria and Nugent score > 3 | Vaginal detection of CT DNA by NAAT | Suggestive symptoms and detection of C. albicans | — |
Mean age ± SD (years) | 26.1 ± 6.3 | 29.3 ± 7.7 | 24.3 ± 3.4 | 27.8 ± 7.2 | 0.08 |
Mean BMI ± SD (kg/m2) | 23.8 ± 2.4 | 22.9 ± 2.4 | 23.6 ± 1.8 | 23.0 ± 2.0 | 0.38 |
Amsel criteria | |||||
Creamy gray discharge | 0/21 (0.0%) | 17/20 (85.0%) | 0/20 (0.0%) | 0/18 (0.0%) | <0.0001 |
Mean vaginal pH value | 4.1 ± 0.3 | 4.8 ± 0.4 | 4.2 ± 0.4 | 4.3 ± 0.5 | <0.0001 |
Positive Whiff testa | 5/21 (23.8%) | 10/20 (50.0%) | 4/20 (20.0%) | 3/18 (16.7%) | 0.07 |
Clue cells present | 1/21 (4.7%) | 19/20 (95.0%) | 3/20 (15.0%) | 5/18 (27.8%) | <0.0001 |
Nugent score | |||||
0–3 | 16/21 (76.2%) | 0/20 (0.0%) | 13/20 (65.0%) | 7/18 (38.9%) | <0.0001 |
4–6 | 5/21 (23.8%) | 8/20 (40.0%) | 7/20 (35.0%) | 11/18 (61.1%) | 0.11 |
7–10 | 0/21 (0.0%) | 12/20 (60.0%) | 0/20 (0.0%) | 0/18 (0.0%) | <0.001 |
