Table 3 Molecular Signatures Database (MSigDB) GO Ontology pathways enriched with hippocampal atrophy over 2 years from baseline.

From: Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Pathway (n = 7)

# of genes/set size

Corrected p-value

Cellular Morphogenesis During Differentiation

33/49

0.0082

Regulation of Anatomical Structure Morphogenesis

18/25

0.0082

Neurite Development

34/53

0.0082

Axonogenesis

30/43

0.013

Cell-Cell Adhesion

54/86

0.013

Neuron Development

40/61

0.050

Transmembrane Receptor Protein Phosphatase Activity

15/19

0.050

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