Figure 3
From: Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapy
FATP1 is downregulated in BCCs treated with PHTPP. BCCs were cultured in control (baseline culture medium represented by the dot line), control DMSO, estradiol and/or C18 conditions, in the presence or absence of PHTPP (A,C) and in the presence or absence of MPP and Fulvestrant (B,D), being analyzed by flow cytometry. Values are referenced to control/DMSO conditions within each cell line. Biological triplicates were tested, only adherent cells were analyzed and dead cells in culture media were discarded. Results are shown as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. (*) represents the statistical analysis in relation to control condition and (#) represents the statistical analysis in relation to DMSO condition. One-way ANOVA with Dunnett’s multiple comparisons test.
