Figure 7
Increased apoptosis in the lungs of SCT−/− mice. (A) TUNEL staining of the lungs shows increased apoptosis in SCT−/− mice compared with C57BL/6N mice (B) TUNEL/CD31 double staining in the lung sections of SCT−/− mice showing an apoptotic endothelial cell [yellow arrow heads] (n = 6). (C) Caspase-3, an indicator of apoptosis, staining from control and SCT−/− mice lungs showing higher caspase-3 positive cells in SCT−/− lungs (n = 5/group)28. (D) Increased apoptotic cell count in SCT−/− mice (from 6 different sections from each mouse, n = 6/group) *p < 0.05.
