Table 2 Multivariable regression analysis with factors associated with the children and caregivers’ quality of life.

From: Factors influencing quality of life in children with atopic dermatitis and their caregivers: a cross-sectional study

Variables

Children HRQOL

Caregivers RAND 36

IDQOL

CDLQI

Physical health

Mental health

IRR

95% CI

P-value

IRR

95% CI

P-value

IRR

95% CI

P-value

IRR

95% CI

P-value

Age of child (years)

1.02

[0.98, 1.06]

0.44

0.99

[0.98, 1.00]

0.02

1.01

[1.00, 1.01]

0.03

1.00

[0.99, 1.01]

0.44

Gender

Male

1(Ref)

           

Female

1.09

[0.93, 1.27]

0.31

0.99

[0.94, 1.05]

0.80

0.99

[0.96, 1.03]

0.69

1.00

[0.94, 1.06]

0.94

Disease duration (years)

1.01

[0.98, 1.05]

0.51

1.00

[1.00, 1.01]

0.16

1.00

[0.99, 1.00]

0.44

1.00

[0.99, 1.01]

0.60

Disease severity*

Mild

1(Ref)

           

Moderate

1.42

[1.20, 1.67]

p < 0.001

1.08

[1.02, 1.14]

0.01

0.98

[0.94, 1.02]

0.35

0.97

[0.90, 1.05]

0.49

Severe

1.72

[1.32, 2.24]

p < 0.001

1.05

[0.96, 1.15]

0.29

0.94

[0.89, 0.99]

0.03

1.03

[0.93, 1.15]

0.57

Ethnicity

Chinese

1 (Ref)

           

Indian

1.12

[0.91, 1.38]

0.30

1.02

[0.95, 1.11]

0.56

0.93

[0.88, 0.97]

0.003

1.00

[0.90, 1.10]

0.97

Malay

1.28

[0.91, 1.80]

0.15

1.01

[0.94, 1.08]

0.82

0.95

[0.88, 1.02]

0.13

1.03

[0.89, 1.20]

0.65

Others

1.28

[0.90, 1.81]

0.17

1.03

[0.93, 1.14]

0.58

1.03

[0.96, 1.11]

0.41

1.04

[0.88, 1.23]

0.67

Educational attainment

Polytechnic and professional

1 (Ref)

           

Primary and secondary

1.16

[0.90, 1.49]

0.27

1.01

[0.94, 1.09]

0.79

1.01

[0.96, 1.06]

0.72

0.99

[0.90, 1.08]

0.77

University

0.95

[0.79, 1.13]

0.54

0.99

[0.93, 1.05]

0.72

0.99

[0.95, 1.03]

0.58

0.99

[0.92, 1.07]

0.82

Number of children in family

1.00

[0.90, 1.11]

0.95

1.02

[0.98, 1.05]

0.42

0.99

[0.97, 1.01]

0.47

0.97

[0.93, 1.01]

0.19

Type of housing

HDB 1–3 rooms

1 (Ref)

           

HDB 4–5 rooms

0.95

[0.71, 1.28]

0.76

1.01

[0.94, 1.10]

0.73

1.04

[0.98, 1.10]

0.21

1.09

[0.97, 1.23]

0.17

Private housing (condo, landlord)

1.01

[0.71, 1.44]

0.95

1.01

[0.92, 1.11]

0.84

1.09

[1.02, 1.17]

0.01

1.10

[0.96, 1.26]

0.19

Children’s HRQOL~

      

0.99

[0.99, 1.00]

p < 0.001

0.98

[0.97, 0.99]

p < 0.001

  1. IRR: incidence rate ratio; CI: confidence interval.
  2. *Missing data: Disease severity, n = 46; Type of housing, n = 2.
  3. ~HRQOL: disease-specific HRQOL of patients with AD was measured using IDQOL and CDLQI.
Back to article page