Figure 4

Homo sapiens Hsp90 binding site with inhibitors and interaction types. (a) Homo sapiens Hsp90 binding site with GA (orange), 17-AAG (blue) and 17-DMAG (magenta). (b) GA (orange), (c) 17-AAG (blue) and (d) 17-DMAG (magenta) and the Hsp90 residues that formed hydrophobic contacts (green), salt bridges (cyan) and hydrogen bonds (red).