Figure 4

Effects of the amino acid substitutions in aEF1A on aEF1A/aEF2-dependent polyphenylalanine synthesis. P. furiosus 70S ribosomes were incubated with P. horikoshii aEF2 and P. horikoshii wild-type aEF1A (bar 2) or each of the aEF1A mutants (bars 3–9) in the presence of poly(U) and E. coli [14C]Phe-tRNA. The amount of polyphenylalanine synthesized in the 10 min reaction was assayed as described in Materials and Methods. Error bars represent SD values (n = 3).