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Figure 1

From: Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells

Figure 1

NKF feeder cells enable NK cell proliferation. (A) Schema of the NKF based NK cell expansion platform. (B) NKF-expanded NK cells are highly pure. Representative flow plots depicting purity of NK cells in the initial PBMC population and after 2 weeks of expansion. (C) Relative fractions of cell types in 2 week expanded NKF-expanded product, n = 15. (D) Fold expansion of NK cells at the indicated NKF:NK ratios and 200U/ml IL-2 after 3 weeks, n = 4. (E) Fold expansion of NK cells at the indicated IL-2 concentrations and NKF cells at a 5:1 ratio after 3 weeks:NK, n = 5. Data represents mean +/− SEM. *p < 0.05.

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