Figure 3

mbIL-21 signaling in NKF-NK cells leads to marked changes in cell surface phenotype. Expression of NK activating receptors (A), inhibitory receptors (B), adhesion receptors (C), NK terminal differentiation receptors (D), and trafficking receptors (E) on IL-2-NK and 2 week expanded NKF-NK cells were measured by flow cytometry, n = 4. Horizontal dotted lines on the plots represent no fold change in the expression of the surface receptor. Data represents mean +/− SEM. *p < 0.05, **p < 0.01, ***p < 0.001.