Table 1 Demographic and Clinical Characteristics of People Screened with Chest X-ray and Xpert MTB/RIF.
Overall | Nepal | Cameroon | |||||||
|---|---|---|---|---|---|---|---|---|---|
Xpert Positive | Xpert Negative | Total | Xpert Positive | Xpert Negative | Total | Xpert Positive | Xpert Negative | Total | |
N | 109 | 1087 | 1196 | 94 | 421 | 515 | 15 | 666 | 681 |
Age (median [IQR]) | 36 [25, 47] | 48 [31, 61] | 46 [30, 61] | 38 [25, 48.75] | 47 [29, 62] | 45 [28, 61] | 33 [25.50, 38] | 48 [32, 61] | 47 [32, 61] |
Sex = F/M (%) | 32/77 (29.4/70.6) | 614/473 (56.5/43.5) | 646/550 (54.0/46.0) | 27/67 (28.7/71.3) | 200/221 (47.5/52.5) | 227/288 (44.1/55.9) | 5/10 (33.3/66.7) | 414/252 (62.2/37.8) | 419/262 (61.5/38.5) |
Cough (%) | 105 (96.3) | 632 (58.1) | 737 (61.6) | 93 (98.9) | 368 (87.4) | 461 (89.5) | 12 (80) | 264 (39.6) | 276 (40.5) |
Fever (%) | 76 (69.7) | 444 (40.8) | 520 (43.5) | 68 (72.3) | 218 (51.8) | 286 (55.5) | 8 (53.3) | 226 (33.9) | 234 (34.4) |
Weight loss (%) | 74 (67.9) | 550 (50.6) | 624 (52.2) | 62 (66) | 150 (35.6) | 212 (41.2) | 12 (80) | 400 (60.1) | 412 (60.5) |
Night Sweats (%) | 37 (33.9) | 269 (24.7) | 306 (25.6) | 29 (30.9) | 83 (19.7) | 112 (21.7) | 8 (53.3) | 186 (27.9) | 194 (28.5) |
TB treatment history (%) | |||||||||
Yes | 89 (81.7) | 982 (90.3) | 1071 (89.5) | 20 (21.3) | 76 (18.1) | 96 (18.6) | 0 (0) | 22 (3.3) | 22 (3.2) |
No | 0 (0.0) | 7 (0.6) | 7 (0.6) | 74 (78.7) | 345 (81.9) | 419 (81.4) | 15 (100) | 637 (95.6) | 652 (95.7) |
Unknown | 20 (18.3) | 98 (9.0) | 118 (9.9) | 0 (0) | 7 (1.1) | 7 (1) | |||
HIV status (%) | |||||||||
Negative | 17 (15.6) | 254 (23.4) | 271 (22.7) | 9 (9.6) | 50 (11.9) | 59 (11.5) | 8 (53.3) | 204 (30.6) | 212 (31.1) |
Positive | 10 (9.2) | 28 (2.6) | 38 (3.2) | 4 (4.3) | 3 (0.7) | 7 (1.4) | 6 (40) | 25 (3.8) | 31 (4.6) |
Unknown | 82 (75.2) | 805 (74.1) | 887 (74.2) | 81 (86.2) | 368 (87.4) | 449 (87.2) | 1 (6.7) | 437 (65.6) | 438 (64.3) |
AFB positive (%) | 76 (70.4) | 2 (0.2) | 78 (6.6) | 67 (71.3) | 1 (0.2) | 68 (13.2) | 9 (64.3) | 1 (0.2) | 10 (1.5) |
Xpert positive (%) | 109 (100.0) | 0 (0.0) | 109 (9.1) | 94 (100) | 0 (0) | 94 (18.3) | 15 (100) | 0 (0) | 15 (2.2) |
CAD4TB (median [IQR]) | 86 [75, 99] | 45 [25, 54] | 46 [28, 59] | 86 [77, 99] | 48 [25, 69] | 54 [40.5, 79.5] | 77 [58, 99] | 44 [25, 49] | 44 [25, 50] |
Lunit (median [IQR]) | 0.99 [0.97, 0.99] | 0.08 [0.01, 0.51] | 0.10 [0.01, 0.80] | 0.99 [0.97, 0.99] | 0.37 [0.05, 0.90] | 0.69 [0.09, 0.96] | 0.97 [0.90, 0.98] | 0.03 [0.01, 0.15] | 0.03 [0.01, 0.18] |
qXR (median [IQR]) | 0.90 [0.82, 0.94] | 0.17 [0.10, 0.36] | 0.19 [0.11, 0.50] | 0.92 [0.84, 0.94] | 0.30 [0.12, 0.65] | 0.44 [0.14, 0.82] | 0.78 [0.64, 0.86] | 0.14 [0.09, 0.23] | 0.15 [0.10, 0.24] |
Senior Radiologist (Nepal) = Normal CXR (%) | 4 (4.3) | 203 (48.2) | 207 (40.2) | ||||||
Junior Radiologist & Residents (Nepal) = Normal CXR (%) | 12 (12.8) | 290 (68.9) | 302 (58.6) | ||||||
Radiologist (Cameroon) = Normal CXR (%) | 3 (20) | 495 (74.3) | 498 (73.1) | ||||||
Teleradiology Company (Cameroon) = Normal CXR (%) | 3 (20) | 494 (74.2) | 497 (73.0) | ||||||
