Table 2 Administration of [68Ga]Ga-DO3A-S01-GCG and study drug for the test-retest and receptor occupancy studies.
From: Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates
ID | NHP 8 | NHP 9 | NHP 10 | NHP 11 | NHP 12 | |
|---|---|---|---|---|---|---|
Weight | 3.9 | 6.1 | 4.0 | 6.4 | 4.5 | |
Type | T/R | T/R | T/R | R.O. | R.O. | |
Scan 1 | µg/kg | 0.041 | 0.029 | 0.086 | 0.034 | 0.043 |
MBq/kg | 0.7 | 0.5 | 0.3 | 0.7 | 0.7 | |
Study drug | 1 mL PBS | 1 mL PBS | 1 ml PBS | 30 µg/kg GCGR agonist in PBS | 30 µg/kg GCGR agonist in PBS | |
Scan 2 | µg/kg | 0.033 | 0.034 | 0.069 | 0.042 | 0.051 |
MBq/kg | 0.5 | 0.5 | 0.2 | 0.6 | 0.9 |
