Figure 7
From: Down-regulation of TUFM impairs host cell interaction and virulence by Paracoccidioides brasiliensis
Viability of PbTufM aRNA was affected in oxidative stress condition. (A) The yeast viability of PbWT, PbEV, PbTufM aRNA treated with different concentrations of H2O2 for 1 h by CFU assay; **p < 0.005 when compared to PbWT, ##p < 0.005 when compared to PbEV and ###p < 0.0001 when compared to PbEV. (B) Interaction assay of P. brasiliensis and macrophage cells. Yeast cell viability after 2 h of macrophage infection (total infection- adhesion and invasion process; and invasion process) was evaluated based on the number of recovered CFU. *p < 0.005 when compared PbTufM aRNA with PbWT and PbEV.
