Figure 4 | Scientific Reports

Figure 4

From: Clostridium difficile clade 3 (RT023) have a modified cell surface and contain a large transposable island with novel cargo

Figure 4

023_CTnT shows sequence identity with C. difficile and human microbiome genomes. Regions within 023_CTnT are found within other strains of C. difficile and human microbiome genomes. (a) Schematic of the three sequential putative transposons within 023_CTnT in CD305; 023_CTn1, 023_CTn2, 023_CTn3. Regions of homology with strain 630 and UHL-19 transposons are indicated below each RT023 transposon. Gene colours indicate putative functions: pale grey, serine recombinase; grey, transposable element/plasmid conjugation; blue, surface proteins and cell wall regulation; green, DNA associated and regulators; red, ABC transporters; purple, signal transduction; pink, biosynthesis/metabolism; yellow, various functional proteins; white, unknown function. (b) BLASTn analysis of sequence coverage of 023_CTnT. Each sub-element is represented by a shaded grey box with the serine recombinases shown above indicating the predicted junction between each sub-element. Sequence identities of each species is indicated by a black bar representing >70% sequence identity.

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