Scientific Reports

Table 11 MHC-I -peptide docking scores of selected CTL epitopes.

From: In silico/In vivo analysis of high-risk papillomavirus L1 and L2 conserved sequences for development of cross-subtype prophylactic vaccine

Epitope (Type)	HLA A0101		HLA A0201		HLA A0301		HLA A2402		HLA A1101		HLA B0702		HLA B0801		HLA B2705		HLA B3501		HLA B5101		Average
Epitope (Type)	C.D*	I.S*	C.D	I.S	C.D	I.S	C.D	I.S	C.D	I.S	C.D	I.S	C.D	I.S	C.D	I.S	C.D	I.S	C.D	I.S	C.D	I.S
L1^12–21 (16)	62.70	262	48.87	216	214.7	215	67.20	240	74.46	229	123.04	275	59.94	250	51.52	239	166.52	296	200.92	322	106.79	254.4
L1^12–21 (18)	63.52	256	44.63	221	90.0	212	80.77	238	40.71	236	73.88	285	58.79	260	200.4	253	142.3	300	72.66	336	86.77	259.7
L1^114–125 (16)	31.43	208	96.97	229	52.27	174	64.62	185	47.22	198	42.94	198	63.84	206	74.77	210	97.73	199	84.57	194	65.64	200.1
L1^104–115 (18)	93.03	207	255.2	231	64.10	176	40.71	180	69.53	175	68.26	188	57.74	208	82.24	186	38.35	199	48.11	212	81.73	196.2
L1^114–125 (18)	70.28	207	52.22	231	81.57	176	67.66	180	70.79	175	105.7	188	74.03	208	111.9	199	71.94	185	61.52	212	76.75	196.1
L1^411–421 (16)	86.44	210	49.32	216	28.77	162	57.40	184	38.22	177	73.79	180	48.97	201	41.36	167	46.61	191	29.67	197	49.75	188.5
L1^414–425 (18)	69.15	186	80.12	226	32.33	170	47.60	193	45.81	188	54.46	186	86.69	198	49.10	186	71.61	210	116.21	186	65.01	192.9
L1^460–470 (16)	34.38	244	319.1	244	91.4	244	71.11	233	62.62	242	41.82	256	96.85	286	64.73	251	53.76	280	56.76	258	94.93	251.8
L1^461–471 (18)	49.32	215	71.94	263	134.6	211	58.35	212	68.53	214	100.2	229	39.65	238	46.39	224	66.01	253	184.38	232	81.94	229.1
L2^11–20 (16)	22.54	170	99.89	155	70.24	147	38.76	156	119.5	152	23.31	182	108.6	175	95.11	195	100.0	198	43.29	185	74.14	171.5
L2^11–20 (18)	30.70	175	101.5	156	73.11	145	33.14	157	64.31	155	43.48	182	44.14	171	68.18	190	121.3	199	56.07	188	63.60	171.8
L2^60–71 (18)	31.70	176	41.61	167	32.51	161	40.97	172	37.48	179	90.20	203	66.10	199	42.57	190	75.45	220	51.26	202	50.98	186.9
L2^280–291(16)	79.13	240	42.95	204	11.33	185	30.04	210	148.6	198	72.19	204	66.63	224	275.2	197	20.27	212	82.55	197	82.89	207
L2^273–284(18)	44.79	235	49.99	199	35.35	186	50.91	206	20.74	201	43.92	200	118.9	217	80.86	195	53.13	195	363.6	184	86.23	201.7
L2^293–303(16)	27.98	170	52.31	176	62.58	180	43.49	177	56.57	179	103.4	220	62.86	199	48.09	190	69.012	185	50.69	189	57.70	186.5
L2^286–296(18)	18.79	233	44.04	195	141.7	175	31.84	182	40.80	185	42.40	219	131.2	234	26.61	202	73.97	199	48.86	191	60.03	201.5

*higher rate shows better quality of peptide-MHC interactions.

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