Table 3 B-cell epitope identification of HPV L1 & L2 conserved regions.

From: In silico/In vivo analysis of high-risk papillomavirus L1 and L2 conserved sequences for development of cross-subtype prophylactic vaccine

Protein Name

Regions

B Cell Epitope

Score*

L1

8–22 (Type 16)

EATVYLPPVPVSKVV

1.000

8–22(Type 18)

DNTVYLPPPSVARV

0.961

119–132 (Type 16)

GHPLLNKLDDTENA

0.998

119–132 (Type 18)

GHPFYNKLDDTESS

0.999

307–320 (Type 16)

FNKPYWLQRAQGHN

0.999

315–328 (Type 18)

KAQGHNNGVCWHNQ

0.976

408–421 (Type 16)

PPPGGTLEDTYRFV

1.000

404–417 (Type 18)

NFGVPPPPTTSLVD

1.000

454–467 (Type 16)

KFSADLDQFPLGRK

0.999

547–570 (Type 18)

SLDLDQYPLGRKFL

0.976

L2

25–38 (Type 16)

AGTCPPDIIPKVEG

0.927

22–35 (Type 18)

KQSGTCPPDVVPKV

1.000

100–113 (Type 16)

PSDPSIVSLVEETS

1.000

94–107 (Type 18)

EPVGPTDPSIVTLI

1.000

57–70 (Type 16)

GLGIGTGSGTGGRT

1.000

56–69 (Type 18)

GLGIGTGSGTGGRT

1.000

289–302 (Type 16)

LHRPALTSRRTGIR

0.800

282–295 (Type 18)

LHRPALTSRRGTVR

0.870

  1. *Higher rates show better quality of epitope identification.