Figure 4 | Scientific Reports

Figure 4

From: Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome

Figure 4

L. brevis altered plasma ornithine and arginine. (A) Sparse partial least square discriminant analysis (sPLS-DA) plot displays HFC (n = 10; red), DPC6108 (n = 10; green) and DSM32386 (n = 10; purple) samples. (B) Plot metabolite loadings graph displaying key metabolite differences between groups. Quantitative data is displayed for the metabolites which were significantly altered by DPC6108 or DSM32386; this included the biogenic amine ornithine (C) and amino acid arginine (D). Orn:Ornithine, Arg:Arginine, Met-SO:Methioninesulfoxide, Glu:Glutamate, alpha AAA:alpha Aminoadipic Acid, Met:Methionine, Phe:Phenylalanine, Gln:Glutamine, HFC: high fat control, DPC6108: L. brevis DPC6108, DSM32386: L. brevis DSM32386. *q < 0.05 treatment vs HFC, **q < 0.01 treatment vs HFC. Plots depict individual replicates with mean and SEM.

Back to article page