Figure 2
IgG response to influenza-A strains in gingival crevicular fluid correlates with serum HAI titre. (a) Graph panels show the correlation of serum HAI titre at Day 0 (left panel) and Day 28 (right panel) with IgG T/N ratio measured in gingival crevicular fluid (GCF) against A/H1N1. (b) Graph panels show the correlation of serum HAI titre at Day 0 (left panel) and Day 28 (right panel) with IgG T/N ratio measured in GCF against A/H3N2. (c) Graph panels show the Day 28 fold change in GCF IgG T/N against, left panel, A/H1N1, and right panel, A/H3N2 in HC, E-HIV and C-HIV. (d) Graph panels show the comparison of the fold change at Day 28 in GCF IgG T/N ratio in serum HAI titre responders (R) and non-responders (NR), to left panel, A/H1N1, and right panel, A/H3N2. (e) Graph panels show the comparison of the fold change at Day 28 in GCF IgG T/N ratio in those seroprotected (SP) and non-seroprotected (NSP) at baseline, left panel, A/H1N1, and right panel, A/H3N2. Correlations were calculated using Spearman’s rank correlation coefficient (rs). p values indicate results of Kruskal-Wallis test (below graph) and Dunn’s multiple comparison test (above graph) for multiple comparisons or results of the Mann-Whitney U test (above graph). Individual data points are shown on graph panels with lines drawn at the median: HC, filled green circles; E-HIV, filled orange circles; C-HIV, open orange circles.
