Table 4 Kinetic constants of wild-type (wt) PTPRR and actPTPRR, assayed with pNPP.

From: Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals

Enzyme

kcat [s−1]

KM [mM]

kcat/KM [mM−1s−1]

wt PTPRR

3.61 ± 0.05

0.84 ± 0.07

4.4 ± 0.4

actPTPRR

0.90 ± 0.06

2.6 ± 0.4

0.35 ± 0.06

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