Figure 1 | Scientific Reports

Figure 1

From: TGF-β1-induced HSP47 regulates extracellular matrix accumulation via Smad2/3 signaling pathways in nasal fibroblasts

Figure 1

HSP47 expression in nasal tissues. (A) HSP47 mRNA expression analyzed using real-time PCR. Tissue from CRSsNP patients showed significantly higher level of HSP47 expression relative to nasal mucosa from the normal control (p = 0.0067) and patients with CRSwNP (2.30 ± 0.75; p = 0.048, Kruskal-Wallis 1-way ANOVA). (B) The correlation between Lund-McKay score and HSP47 expression in normal control and CRS patients (R square = 0.2391). (C) The correlations between HSP47 expression and extracellular matrix-related makers in the normal control (n = 4) and CRS patients (n = 33). Data are expressed as the mean ± SEM of three independent experiments. *p < 0.05 vs. Normal.

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