Figure 6
From: Molecular signatures of retinal ganglion cells revealed through single cell profiling
Voltage-gated channel genes detected in subsets of RGCs. The expression of potassium and sodium channel subunits were queried in our tdTomato+ (A) and physiologically characterized RGCs (B) and displayed by heatmap. Four of these ion channel genes were detected by ISH: Kcnc2 (C), Kcnab2 (D), Scn2a1 (E), and Scn1a (F). Voltage-gated channel genes were then explored for expression among scRNA-seq data of 8 physiologically characterized cells and visualized on a heatmap (G). Scn4b expression was further examined by section ISH (H) and flat-mount ISH (I). Scale bars represent 100 µm.
