Table 3 Pharmacokinetic parameters of cordycepin following intravenous administration of cordycepin.

From: A novel nucleoside rescue metabolic pathway may be responsible for therapeutic effect of orally administered cordycepin

Route of administration

Intravenous

Dose (mg/kg)

8

20

C0 (ng/mL)

890 ± 576

12298 ± 8844

AUC0→t (ng·h/mL)

196 ± 94

232 ± 106

AUC0→t/Dose (ng·h·kg/mL/mg)

25 ± 12

12 ± 5

CL (L/h/kg)

103 ± 52

91 ± 41

  1. C0, concentration extrapolated to time zero; AUC0→t, area under the concentration-time curve from time zero to the last time point observed; CL, clearance.
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