Figure 4 | Scientific Reports

Figure 4

From: Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts

Figure 4

Validation of NGS using RT-qPCR. Expression levels of selected miRNAs that are differentially expressed based on NGS data, as determined by RT-qPCR. (a) miRNAs up-regulated in Oct4+ hDFs: mir-183, mir-302 cluster members, and miR-9-5p. (b) miRNAs down-regulated in Oct4+ hDFs: miR-34c-5p, miR-193a-5p, miR-424-5p, miR-503-5p, miR-143-3p and miR-145-5p. The results are shown as expression relative to corresponding control GFP+ hDFs. Error bars represent ± SD.

Back to article page