Table 3 Abnormalities in 157 women with Turner syndrome treated (GH+) and not treated with growth hormone in childhood (GH−), as revealed in their medical histories. V – absolute values, (%) – percent.
From: Childhood growth hormone treatment in women with Turner syndrome - benefits and adverse effects
Parameter | GH + (n = 33) | GH− (n = 124) | GH + vs GH− P - value | ||
---|---|---|---|---|---|
V | (%) | V | (%) | ||
Skin diseases | 9 | 27.3 | 30 | 24.2 | 0.7 |
Ingrowing nails | 12 | 36.4 | 23 | 18.5 | 0.028 |
Childhood lymphedema | 15 | 45.5 | 28 | 21.7 | 0.0068 |
Feeding problems during infancy | 23 | 69.7 | 61 | 49.2 | 0.036 |
Third tonsil adenotomy | 10 | 30.3 | 36 | 29 | 0.9 |
Dental braces | 6 | 18.5 | 23 | 23.4 | 0.5 |
Otitis media | 24 | 72.7 | 84 | 67.7 | 0.6 |
Surgery for otitis media | 3 | 9.1 | 15 | 12.1 | 0.6 |
Heart defect(s) | 7 | 21.2 | 12 | 9.7 | 0.072 |
Urologic surgery | 0 | 0 | 5 | 4 | 0.2 |
Urinary system malformations | 10 | 30.3 | 18 | 14.5 | 0.035 |
Conservative kidney management | 12 | 36.4 | 35 | 28.2 | 0.4 |
History of vision defects | 18 | 54.5 | 76 | 61.3 | 0.5 |
History of thyroid diseases | 5 | 15.2 | 23 | 18.5 | 0.7 |
Diabetes mellitus | 2 | 6.1 | 8 | 6.5 | 0.9 |