Figure 4 | Scientific Reports

Figure 4

From: The Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis

Figure 4

Katanin p60 haploinsufficiency does not affect long-term potentiation at the dentate gyrus. (A) Long-term potentiation (LTP) at the medial perforant pathway following a high-frequency stimulation protocol. (B) Both genotypes showed similar synaptic potentiation based on the mean EPSP slope during the last 5 min of recordings. Insets show analogue traces of EPSPs recorded during baseline and 30 min after high-frequency stimulation. Scale bars: 2 mV/2 ms. (C) There were no significant EPSP slope differences in basal conditions between genotypes. (D,E) Sholl analysis of dentate gyrus granule cells show no significant differences in dendritic arborization between genotypes.

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