Figure 1

Factors involved in cardiomyocyte proliferation. A brief review of factors identified in rodents or using human iPSCs as regulators of cardiomyocyte proliferation. Circles, squares, and triangles show the model system used, experiment, and proliferation detection method, respectively. Arrows show activating factors, blunt arrowheads show inhibitory factors, and lines show factors determined to have no effect. A combination of two types of arrows for the same factor shows conflicting results. Numbers denote the studies for each factor, which can be found in the supplementary references.