Table 3 Genetic polymorphism and grade of sedation: (A) MDR1, (B) CYP3A5.

From: Influence of midazolam-related genetic polymorphism on conscious sedation during upper gastrointestinal endoscopy in a Korean population

 

Ramsay score ≤3

(n = 85)

Ramsay score ≥4

(n = 15)

P-value

(A) MDR1

H1 TTT

45

(52.9%)

6

(40.0%)

0.355

H2 TGC

33

(38.8%)

7

(46.7%)

0.568

H3 CGC

32

(37.6%)

4

(26.7%)

0.414

H4 CAC

27

(31.8%)

7

(46.7%)

0.261

H5 TTC

7

(8.2%)

1

(6.7%)

1.000

H6 CGT

3

(3.5%)

3

(20.0%)

0.042

H7 TAT

2

(2.4%)

0

(0%)

1.000

(B) CYP3A5

*3/*3

49

(57.6%)

8

(53.3%)

0.071

*1/*3

28

(32.9%)

7

(46.7%)

0.145

*1/*1

8

(9.4%)

0

(0%)

0.476

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