Figure 5
Male and female offspring metabolic characteristics on postnatal ND or postnatal HFD. Weekly weights from 13–24 weeks of age (A) in male and (B) in female offspring, Male: Control-ND (n = 10), Pre-ND (n = 12), P/G-ND (n = 4), Control-HFD (n = 12), Pre-HFD (n = 14), P/G-HFD (n = 10); Female: Control-ND (n = 6), Pre-ND (n = 6), Control-HFD (n = 17), Pre-HFD (n = 7), P/G-HFD (n = 3). *p < 0.05 GTT and AUC at 22 weeks for groups with postnatal ND (C) in male and (D) in female offspring, Male: Control-ND (n = 10), Pre-ND (n = 12), P/G-ND (n = 4); Female: Control-ND (n = 15), Pre-ND (n = 6), P/G-ND (n = 9). GTT and AUC at 22 weeks for groups with postnatal HFD (E) in male and (F) in female offspring. Male: Control-HFD (n = 11), Pre-HFD (n = 14), P/G-HFD (n = 10); Female: Control-ND (n = 17), Pre-ND (n = 7), P/G-ND (n = 3). *p < 0.05. Among the male groups with postnatal HFD, there was a significant increase in body weight, greatest for Pre group from week 20–24. For IPGTT, P/G with postnatal HFD had the worst glucose tolerance.
