Figure 5 | Scientific Reports

Figure 5

From: Induction of detrusor underactivity by extensive vascular endothelial damages of iliac arteries in a rat model and its pathophysiology in the genetic levels

Figure 5

Increased apoptosis in the bladder tissues by the chronic bladder ischemia. Representative images of staining to detect apoptotic cells (green) in the bladder endothelium. (a) and muscle layer (b) of animals in the rat of indicated groups (magnification ×400, scale bar = 20 μm); (c,d) Quantification of the staining results. Percentage of apoptotic cells was quantified by calculating the ratio of apoptotic cells (TUNEL-positive) to total cells (DAPI-stained nuclei). All data are presented as mean ± SEM (n = 20). *p < 0.05, **p < 0.01, ***p < 0.001 compared to the sham group; #p < 0.05, ##p < 0.01, ###p < 0.001 compared to the AI-30 group according to a one-way ANOVA with the Bonferroni post-hoc test. Source data with exact p-values and number of replicates can be found in the Supplementary Dataset.

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