Table 1 Clinical and demographic characteristics of patients with for-cause biopsy.
Variables | Total (n = 39) | NR (n = 8) | TCMR (n = 11) | ABMR (n = 20) | P-value |
|---|---|---|---|---|---|
Mean age, y (SD) | 43.7 (12.8) | 45.5 (15.4) | 46.0 (9.8) | 42.6 (13.3) | 0.735 |
Female sex, n (%) | 8 (20.5) | 2 (25.0) | 1 (9.1) | 5 (25.0) | 0.789 |
Body mass index, kg/m2 (SD) | 22.4 (2.7) | 21.5 (3.7) | 21.6 (2.7) | 22.8 (2.4) | 0.475 |
Deceased donor, n (%) | 13 (33.3) | 3 (37.5) | 3 (27.3) | 7 (35.0) | 0.806 |
Previous transplant, n (%) | 9 (23.1) | 3 (37.5) | 1 (9.1) | 5 (25.0) | 0.715 |
Time to biopsy, month (SD) | 23.1 (16.3) | 10.5 (14.4) | 24.3 (12.9) | 27.4 (16.7) | 0.03 |
Cause of ESRD, n (%) | |||||
Glomerular | 5 (12.8) | 2 (25.0) | 0 | 3 (15.0) | |
Diabetes | 6 (15.4) | 1 (12.5) | 3 (27.3) | 2 (10.0) | |
Hypertension | 4 (10.3) | 2 (25.0) | 0 | 2 (10.0) | |
FSGS | 1 (2.6) | 1 (12.5) | 0 | 0 | |
Other | 17 (43.6) | 2 (25.0) | 6 (54.5) | 9 (45.0) | |
Unknown | 6 (15.4) | 0 | 2 (18.2) | 4 (20.0) | |
ABO-incompatible KT | 10 (25.6) | 3 (37.5) | 3 (27.3) | 4 (20.0) | 0.625 |
Serum creatinine at the time of biopsy, mg/dL (SD) | 2.7 (1.9) | 2.7 (2.5) | 2.3 (0.8) | 2.9 (2.1) | 0.746 |
PRA > 10%, n (%) | 18 (46.2) | 5 (62.5) | 2 (18.2) | 11 (55.0) | 0.853 |
DSA at the time of biopsy, n (%) | 22 (56.4) | 4 (50.0) | 3 (27.3) | 15 (75.0) | 0.088 |
CNI at the time of biopsy, n (%) | 0.789 | ||||
Cyclosporine | 8 (20.5) | 0 | 5 (45.5) | 3 (15.0) | |
Tacrolimus | 31 (79.5) | 8 (100) | 6 (54.5) | 17 (85.0) | |
Follow-up after biopsy, month (SD) | 46.7 (19.1) | 38.1 (20.7) | 49.1 (14.5) | 48.8 (20.5) | 0.317 |
