Table 2 Comparison of histopathologic characteristics according to histologic diagnosis.

From: CD56+CD57+ infiltrates as the most predominant subset of intragraft natural killer cells in renal transplant biopsies with antibody-mediated rejection

Variables

Total (n = 39)

NR (n = 8)

TCMR (n = 11)

AmBR (n = 20)

P value

Histopathology, n (%)

    

0.009

   TCMR only

11 (28.2)

0

11 (100)

0

 

   ABMR only

11 (28.2)

0

0

11 (55.0)

 

   ABMR + TCMR

9 (23.1)

0

0

9 (45.0)

 

   No rejection

8 (20.5)

8 (100)

0

0

 

C4d staining, n (%)

    

0.747

   <10%

34 (87.2)

7 (87.5)

9 (81.8)

18 (90.0)

 

   ≥10%, <50%

5 (12.8)

1 (12.5)

2 (18.2)

2 (10.0)

 

   ≥50%

0

0

0

0

 

IFTA, n (%)

    

0.02

   Minimal

7 (17.9)

4 (50.0)

1 (9.1)

2 (10.0)

 

   Mild

16 (41.0)

2 (25.0)

7 (63.6)

7 (35.0)

 

   Moderate-to-severe

16 (41.0)

2 (25.0)

3 (27.3)

11 (55.0)

 

Mean Banff score, mean (SD)

   g

0.79 (0.83)

0.75 (1.04)

0.27 (0.47)

1.1 (0.79)

0.025

   cg

0.31 (0.73)

0.13 (0.35)

0.09 (0.3)

0.5 (0.95)

0.246

   mm

0.15 (0.37)

0.25 (0.46)

0.18 (0.41)

0.1 (0.31)

0.603

   i

1.49 (1.07)

0.5 (0.76)

1.27 (0.91)

2.00 (0.97)

0.001

   ci

1.26 (0.97)

0.5 (0.76)

1.18 (0.75)

1.6 (0.99)

0.019

   t

1.46 (1.02)

0.75 (1.17)

1.64 (0.81)

1.65 (0.99)

0.084

   ct

1.33 (0.90)

0.63 (0.74)

1.27 (0.65)

1.65 (0.93)

0.019

   v

0.05 (0.22)

0.13 (0.35)

0

0.05 (0.22)

0.496

   cv

1.05 (1.03)

0.63 (0.74)

1.27 (1.27)

1.1 (0.97)

0.389

   ah

0.82 (1.02)

0.25 (0.46)

1.36 (1.21)

0.75 (0.97)

0.054

   ptc

1.33 (1.18)

0.5 (1.07)

0.45 (1.04)

2.15 (0.59)

<0.001

   ti

1.9 (0.97)

0.88 (0.64)

1.73 (0.65)

2.4 (0.88)

<0.001

   i-IFTA

1.97 (0.99)

1.38 (1.30)

2.22 (0.97)

2.10 (0.79)

0.146

  1. NR, no rejection; TCMR, T-cell-mediated rejection; ABMR, antibody-mediated rejection; IFTA, interstitial fibrosis and tubular atrophy; SD, standard deviation.