Table 2 Primary association of NCF1 rs201802880 among the GTF2I-NCF1 region SNPs demonstrated by conditional logistic regression analysis.

From: Association of NCF1 polymorphism with systemic lupus erythematosus and systemic sclerosis but not with ANCA-associated vasculitis in a Japanese population

  

rs73366469

rs117026326

rs80346167

rs201802880

P

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

SLE all

before

4.35 × 10−14

2.45 (1.95–3.10)

6.82 × 10–16

2.67 (2.11–3.40)

3.54 × 10−5

1.48 (1.23–1.79)

3.77 × 10−44

3.57 (2.99–4.28)

SSc all

before

0.014

1.45 (1.08–1.95)

0.027

1.41 (1.04–1.92)

0.047

1.28 (1.00–1.59)

2.40 × 10−4

1.50 (1.21–1.87)

Adjusted by rs73366469

SLE all

after

—

—

0.0018

2.31 (1.37–2.94)

0.32

0.88 (0.69–1.13)

5.11 × 10−34

3.41 (2.81–4.17)

SSc all

after

—

—

0.86

1.06 (0.57–1.95)

0.49

1.11 (0.82–1.49)

0.0043

1.44 (1.12–1.84)

Adjusted by rs117026326

SLE all

after

0.45

1.17 (0.70–1.96)

—

—

0.24

0.87 (0.68–1.10)

2.54 × 10−32

3.37 (2.77–4.14)

SSc all

after

0.28

1.39 (0.76–2.50)

—

—

0.35

1.15 (0.86–1.53)

0.0029

1.47 (1.14–1.89)

Adjusted by rs80346167

SLE all

after

5.50 × 10−11

2.69 (2.01–3.62)

6.56 × 10−13

2.96 (2.21–4.00)

—

—

1.63 × 10−41

3.53 (2.95–4.25)

SSc all

after

0.12

1.34 (0.93–1.94)

0.19

1.28 (0.89–1.85)

—

—

9.84 × 10−4

1.46 (1.16–1.82)

Adjusted by rs201802880

SLE all

after

0.29

1.15 (0.88–1.51)

0.24

1.18 (0.89–1.56)

0.56

1.06 (0.87–1.30)

—

—

SSc all

after

0.45

1.14 (0.81–1.60)

0.74

1.06 (0.74–1.52)

0.25

1.16 (0.90–1.48)

—

—

  1. Conditional logistic regression analysis was performed under the additive model using R software. P values (P) and odds ratios (OR) were adjusted for sex. P and OR on rows “before” are before adjustment by any other SNPs. P and OR on rows “after” are adjusted by each SNP. In this table, P values are not adjusted for multiple testing. CI; confidence interval.
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