Table 4 Comparison of FISH results between 2013 and 2018 guidelines.

From: Impact of the 2018 ASCO/CAP guidelines on HER2 fluorescence in situ hybridization interpretation in invasive breast cancers with immunohistochemically equivocal results

FISH status

2013 guidelines (N. %)

2018 guidelines (N. %)

Negative

1406 (77.68)

1479 (81.71)

Equivocal

53 (2.93)

0

Positive

351 (19.39)

331 (18.29)

  1. N: number of cases; FISH: fluorescence in situ hybridization.