Figure 2
Pairwise random effects meta-analysis of randomized controlled trials investigating the effect of statin therapy versus control on the rate of annual eGFR decline. Positive values mean slower eGFR decline for statin users vs non-users, thus favouring statin use. In this forest plot, only 30 RCTs are included that compare a statin intervention vs non-statin control intervention. We thus excluded 13 RCTs that reported only the outcome proteinuria (n = 3), or that compared two statin interventions (n = 10). eGFR, estimated glomerular filtration rate; eze, ezetimibe 10 mg; CI, confidence interval; WMD, weighted mean difference; n, no; y, yes.
