Figure 5

Differentially expressed proteins related to fatty acid metabolism involving β-oxidation in six different 3T3-L1 cells. Proteins down-regulated when compared to those of 2D mono-cultured preadipocytes (>1.5-fold change) are indicated in blue, and up-regulated proteins (>1.5-fold change) are indicated in pink. Boxes from the left to the right represent 2D mono-cultured preadipocytes (2P), 2D mono-cultured adipocytes (2A), 2D co-cultured adipocytes with macrophages (2C), 3D mono-cultured preadipocytes (3P), 3D mono-cultured adipocytes (3A) and 3D co-cultured adipocytes with macrophages (3C). (*Abbreviations: CD36, platelet glycoprotein 4; FABP4, fatty acid-binding protein, adipocyte; ACSF2, acyl-CoA synthetase family member 2, mitochondrial; ACSL1, long-chain-fatty-acid-CoA ligase 1; CPT1A, carnitine O-palmitoyltransferase 1, liver isoform; ACADM, medium-chain specific acyl-CoA dehydrogenase, mitochondrial; HADHα, trifunctional enzyme subunit alpha; HADHβ, trifunctional enzyme subunit beta; ACAA2, 3-ketoacyl-CoA thiolase; ACCA1A, 3-ketoacyl-CoA thiolase A; HSL, hormone-sensitive lipase; ATGL, patatin-like phospholipase domain-containing protein 2; DGAT1, diacylglycerol O-acyltransferase 1; SCD1, stearoyl-CoA desaturase 1).