Figure 3
From: PD-1+ melanocortin receptor dependent-Treg cells prevent autoimmune disease
Cytokine profile in PBMCs from uveitis patients. PBMCs from uveitis patients or healthy donors were cultured for 48 hours in serum free media. After the 48-hour culture the supernatants were collected and cytokines were measured by Bioplex. The cytokines that were significantly different between PBMCs from health controls (HC) and uveitis patients (uveitis) is shown. The proinflammatory cytokines IL-12 (A) for HC (n = 14) and uveitis (n = 22) and IL-23 (B) HC (n = 11) and uveitis (n = 29), and regulatory cytokine IL-10 (C) are shown HC (n = 9) and uveitis (n = 24). Significance was assessed by nonparametric Mann-Whitney U test. Statistical significance (p < 0.05) is designated by *.
