Figure 2

A dose response curve for the recombinant enolase enzyme (40 nM) in the presence of 2.0 nM to 2.0 μM SF2312 (A) and 4.0 nM to 100 μM KSF (B). The IC50 and Ki values of SF2312 and KSF were 18.4 nM (Ki = 3.4 nM) and 7.7 μM (1.4 μM) respectively.