Table 2 Antibacterial Activity of SF2312 and fosfomycin in CAHM media with and without 25 μg/mL of Glucose-6-Phosphate (represented as MIC in μg/mL).

From: Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate

 

Without Glucose-6-Phosphate in the media

With Glucose-6-Phosphate in the media

Microorganism

SF2312

fosfomycin

SF2312

fosfomycin

E. coli ATCC 25922

400

>10

100

1.25

A. baumannii ATCC 19606

>400

>20

>400

>20

S. aureus ATCC 43300

100

20

20

2.5

P. aeruginosa ATCC 27853

50

5

50

5